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1

How do you take your coffee?

Sissung, Tristan M, Huang, Phoebe A, Strope, Jonathan D, Figg, William D

Journal:

The Lancet Oncology

Year:

2019

Language:

english

File:

PDF, 356 KB

english, 2019

2

Stem cell clinics: risk of proliferation

Sissung, Tristan M, Figg, William D

Journal:

The Lancet Oncology

Year:

2020

Language:

english

File:

PDF, 386 KB

english, 2020

3

Pharmacogenomics with red cells: a model to study protein variants of drug transporter genes

Flegel, Willy Albert, Srivastava, Kshitij, Sissung, Tristan Michael, Goldspiel, Barry Ronald, Figg, William Douglas

Journal:

Year:

2020

File:

PDF, 187 KB

2020

4

CYP2D6 polymorphisms and the impact on tamoxifen therapy

Jacob N. Beverage, Tristan M. Sissung, Amy M. Sion, Romano Danesi, William D. Figg

Journal:

Journal of Pharmaceutical Sciences

Year:

2007

Language:

english

File:

PDF, 122 KB

english, 2007

5

Pharmacogenetics of Membrane Transporters: An Update on Current Approaches

Tristan M. Sissung, Caitlin E. Baum, C. Tyler Kirkland, Rui Gao, Erin R. Gardner, William D. Figg

Journal:

Molecular Biotechnology

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

6

Pre-clinical and clinical evaluation of estramustine, docetaxel and thalidomide combination in androgen-independent prostate cancer

William D. Figg, Haiqing Li, Tristan Sissung, Avi Retter, Shenhong Wu, James L. Gulley, Phil Arlen, John J. Wright, Howard Parnes, Kathy Fedenko, Lea Latham, Seth M. Steinberg, Elizabeth Jones, Clara

Journal:

BJU International

Year:

2007

Language:

english

File:

PDF, 292 KB

english, 2007

7

A polymorphism in a transporter of testosterone is a determinant of androgen independence in prostate cancer

Nima Sharifi, Akinobu Hamada, Tristan Sissung, Romano Danesi, David Venzon, Caitlin Baum, James L. Gulley, Douglas K. Price, William L. Dahut, William D. Figg

Journal:

BJU International

Year:

2008

Language:

english

File:

PDF, 168 KB

english, 2008

8

Association of the ABCG2 C421A polymorphism with prostate cancer risk and survival

Erin R. Gardner, Christoph M. Ahlers, Suneet Shukla, Tristan M. Sissung, Sandra B. Ockers, Douglas K. Price, Akinobu Hamada, Robert W. Robey, Seth M. Steinberg, Suresh V. Ambudkar, William L. Dahut, W

Journal:

BJU International

Year:

2008

Language:

english

File:

PDF, 199 KB

english, 2008

9

More than an accessory: implications of type III transforming growth factor-β receptor loss in prostate cancer

Seun Ajiboye, Tristan M. Sissung, Nima Sharifi, William D. Figg

Journal:

BJU International

Year:

2010

Language:

english

File:

PDF, 220 KB

english, 2010

10

The ERCC1 N118N polymorphism does not change cellular ERCC1 protein expression or platinum sensitivity

Rui Gao, Kelie Reece, Tristan Sissung, Eddie Reed, Douglas K. Price, William D. Figg

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2011

Language:

english

File:

PDF, 542 KB

english, 2011

11

Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients

Ilaria Pastina, Elisa Giovannetti, Aldo Chioni, Tristan M Sissung, Francesco Crea, Cinzia Orlandini, Douglas K Price, Claudia Cianci, William D Figg, Sergio Ricci, Romano Danesi

Journal:

Year:

2010

Language:

english

File:

PDF, 275 KB

english, 2010

12

Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropenia

Tristan M. Sissung, Klaus Mross, Seth M. Steinberg, Dirk Behringer, William D. Figg, Alex Sparreboom, Stephan Mielke

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

13

Association of a CYP17 Polymorphism with Overall Survival in Caucasian Patients with Androgen-Independent Prostate Cancer

Akinobu Hamada, Romano Danesi, Douglas K. Price, Tristan Sissung, Cindy Chau, David Venzon, Alex Sparreboom, William L. Dahut, William D. Figg

Journal:

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

14

Clinical pharmacology and pharmacogenetics in a genomics era: the DMET platform

Sissung, Tristan M, English, Bevin C, Venzon, David, Figg, William D, Deeken, John F

Journal:

Pharmacogenomics

Year:

2010

Language:

english

File:

PDF, 3.38 MB

english, 2010

15

Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib

Lokesh Jain, Tristan M Sissung…

Journal:

Journal of Experimental & Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

16

Phase II Study of Satraplatin and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer: A Pharmacogenetic Assessment of Outcome and Toxicity

Figg, William D., Chau, Cindy H., Madan, Ravi A., Gulley, James L., Gao, Rui, Sissung, Tristan M., Spencer, Shawn, Beatson, Melony, Aragon-Ching, Jeanny, Steinberg, Seth M., Dahut, William L.

Journal:

Clinical Genitourinary Cancer

Year:

2013

Language:

english

File:

PDF, 366 KB

english, 2013

17

Integrating pharmacogenetic information and clinical decision support into the electronic health record

Goldspiel, Barry R, Flegel, Willy A, DiPatrizio, Gary, Sissung, Tristan, Adams, Sharon D, Penzak, Scott R, Biesecker, Leslie G, Fleisher, Thomas A, Patel, Jharana J, Herion, David, Figg, William D, Le

Journal:

Journal of the American Medical Informatics Association

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

18

Genetic variation: effect on prostate cancer

Sissung, Tristan M., Price, Douglas K., Del Re, Marzia, Ley, Ariel M., Giovannetti, Elisa, Figg, William D., Danesi, Romano

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2014

Language:

english

File:

PDF, 539 KB

english, 2014

19

cis-1,5-Diaminocyclooctane: the most basic gaseous primary amine?

Poutsma, John C., Andriole, Erica J., Sissung, Tristan, Morton, Thomas Hellman

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 112 KB

english, 2003

20

Phase 1 trial and pharmacokinetic study of the oral platinum analog satraplatin in children and young adults with refractory solid tumors including brain tumors

Akshintala, Srivandana, Marcus, Leigh, Warren, Katherine E., Murphy, Robert F., Sissung, Tristan M., Srivastava, Anjali, Goodspeed, Wendy J., Goodwin, Anne, Brewer, Carmen C., Zalewski, Christopher, K

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 227 KB

english, 2015

21

Estrogen Receptor α and Aromatase Polymorphisms Affect Risk, Prognosis, and Therapeutic Outcome in Men with Castration-Resistant Prostate Cancer Treated with Docetaxel-Based Therapy

Sissung, Tristan M., Danesi, Romano, Kirkland, C. Tyler, Baum, Caitlin E., Ockers, Sandra B., Stein, Erica V., Venzon, David, Price, Douglas K., Figg, William D.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2011

Language:

english

File:

PDF, 377 KB

english, 2011

22

A genomic strategy for predicting androgen receptor activity in prostate tumors

Jonsson, Johann G., Sissung, Tristan, Figg, William D.

Journal:

Cancer Biology & Therapy

Year:

2009

Language:

english

File:

PDF, 1.30 MB

english, 2009

23

Loss of OATP1B3 function causes Rotor syndrome

Pratt, Elias, Sissung, Tristan M., Figg, William D.

Journal:

Cancer Biology & Therapy

Year:

2012

Language:

english

File:

PDF, 760 KB

english, 2012

24

Gene expression analysis enables repositioning of mithramycin for precision medicine inhibition of cancer stem cell signaling in thoracic malignancies

Schrump, David S., Zhang, Mary, Hong, Julie, Shukla, Vivek, Ripley, R. Taylor, Atay, Scott M., Hong, Young, Peer, Cody J., Sissung, Tristan M., Figg, William D.

Journal:

Journal of the American College of Surgeons

Year:

2015

Language:

english

File:

PDF, 55 KB

english, 2015

25

Current Status of Thalidomide and CC-5013 in the Treatment of Metastatic Prostate Cancer

Sissung, Tristan, Thordardottir, Silja, Gardner, Erin, Figg, William

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 238 KB

english, 2009

26

Stromal-epithelial interactions are responsible for prostate tumor progression through an androgen-related mechanism

Sharma, Haveesh, Sissung, Tristan M., Pressler, Heather, Figg, William D.

Journal:

Cancer Biology & Therapy

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

27

Effect of ABCG2 genotype on the oral vioavailability of topotecan

Sparreboom, Alex, Loos, Walter J., Burger, Herman, Sissung, Tristan M., Verweij, Jaap, Figg, II, William, Nooter, Kees, Gelderblom, Hans

Journal:

Cancer Biology & Therapy

Year:

2005

Language:

english

File:

PDF, 576 KB

english, 2005

28

CHIP and gp78-mediated ubiquitination of CYP3A4

Peer, Cody J., Sissung, Tristan M., Figg, II, William D.

Journal:

Cancer Biology & Therapy

Year:

2011

Language:

english

File:

PDF, 706 KB

english, 2011

29

Genetic stability of tumor microenvironment

Danish, Matthew, Sissung, Tristan, K. Price, Douglas, D. Figg, William

Journal:

Cancer Biology & Therapy

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

30

Estrogen Receptor α and Aromatase Polymorphisms Affect Risk, Prognosis, and Therapeutic Outcome in Men with Castration-Resistant Prostate Cancer Treated with Docetaxel-Based Therapy

Sissung, Tristan M., Danesi, Romano, Kirkland, C. Tyler, Baum, Caitlin E., Ockers, Sandra B., Stein, Erica V., Venzon, David, Price, Douglas K., Figg, William D.

Journal:

Molecular Endocrinology

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

31

Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction

Goey, Andrew K. L., Chau, Cindy H., Sissung, Tristan M., Cook, Kristina M., Venzon, David J., Castro, Amaya, Ransom, Tanya R., Henrich, Curtis J., McKee, Tawnya C., McMahon, James B., Grkovic, Tanja,

Journal:

Journal of Natural Products

Year:

2016

Language:

english

File:

PDF, 2.79 MB

english, 2016

32

Phase II Trial of Docetaxel, Bevacizumab, Lenalidomide, and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer

Madan, Ravi A., Karzai, Fatima H., Ning, Yang-Min, Adesunloye, Bamidele A., Huang, Xuan, Harold, Nancy, Couvillon, Anna, Chun, Guinevere, Cordes, Lisa, Sissung, Tristan, Beedie, Shaunna L., Dawson, Na

Journal:

BJU International

Year:

2016

Language:

english

File:

PDF, 246 KB

english, 2016

33

UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation

Peer, Cody J., Goey, Andrew K. L., Sissung, Tristan M., Erlich, Sheryl, Lee, Min-Jung, Tomita, Yusuke, Trepel, Jane B., Piekarz, Richard, Balasubramaniam, Sanjeeve, Bates, Susan E., Figg, William D.

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

34

Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer

Goey, Andrew K. L., Sissung, Tristan M., Peer, Cody J., Trepel, Jane B., Lee, Min-Jung, Tomita, Yusuke, Ehrlich, Sheryl, Bryla, Christine, Balasubramaniam, Sanjeeve, Piekarz, Richard, Steinberg, Seth

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.68 MB

english, 2016

35

Erratum to: Association of a CYP17 Polymorphism With Overall Survival in Caucasian Patients With Androgen-independent Prostate Cancer

Sissung, Tristan M., Venzon, David J., Figg, William D.

Journal:

Year:

2016

Language:

english

File:

PDF, 182 KB

english, 2016

36

ANDROGEN RECEPTOR VARIATION AFFECTS PROSTATE CANCER PROGRESSION AND DRUG RESISTANCE

McCrea, Edel, Sissung, Tristan M., Price, Douglas K., Chau, Cindy H., Figg, William D.

Journal:

Pharmacological Research

Year:

2016

Language:

english

File:

PDF, 629 KB

english, 2016

37

Pharmacogenomics and histone deacetylase inhibitors

Goey, Andrew KL, Sissung, Tristan M, Peer, Cody J, Figg, William D

Journal:

Pharmacogenomics

Year:

2016

Language:

english

File:

PDF, 1004 KB

english, 2016

38

Identification of novel SNPs associated with risk and prognosis in patients with castration-resistant prostate cancer

Sissung, Tristan M, Deeken, John, Leibrand, Crystal R, Price, Douglas K, Ehrlich, Sheryl, Steinberg, Seth M, Liewehr, David J, Dahut, William, Figg, William D

Journal:

Pharmacogenomics

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

39

Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx

Sissung, Tristan M, Ley, Ariel M, Strope, Jonathan D., McCrea, Edel M, Beedie, Shaunna L, Peer, Cody J, Shukla, Suneet, van Velkinburgh, Jennifer C., Reece, Kelie, Troutman, Sarah, Campbell, Tessa, Fe

Journal:

Molecular Cancer Research

Year:

2017

Language:

english

File:

PDF, 4.07 MB

english, 2017

40

Cellular identity crisis: antiandrogen resistance by lineage plasticity

Tuerff, Daniel, Sissung, Tristan, Figg, William D.

Journal:

Cancer Biology & Therapy

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

41

Carfilzomib and lenalidomide response related to VEGF and VEGFR2 germline polymorphisms

Sissung, Tristan M., Peer, Cody J., Korde, Neha, Mailankody, Sham, Kazandjian, Dickran, Venzon, David J., Landgren, Ola, Figg, William D.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2017

Language:

english

File:

PDF, 416 KB

english, 2017

42

Discussing the Predictive, Prognostic, and Therapeutic Value of Germline DNA-Repair Gene Mutations in Metastatic Prostate Cancer Patients

Hauke, Ralph J., Sissung, Tristan M., Figg, William D.

Journal:

Cancer Biology & Therapy

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

43

Pharmacogenomics Implementation at the National Institutes of Health Clinical Center

Sissung, Tristan M., McKeeby, Jon W., Patel, Jharana, Lertora, Juan J., Kumar, Parag, Flegel, Willy A., Adams, Sharon D., Eckes, Ellen J., Mickey, Frank, Plona, Teri M., Mellot, Stephanie D., Baugher,

Journal:

Journal of Clinical Pharmacology

Year:

2017

Language:

english

File:

PDF, 728 KB

english, 2017

44

Expression of OATP Family Members in Hormone-Related Cancers: Potential Markers of Progression

Pressler, Heather, Sissung, Tristan M., Venzon, David, Price, Douglas K., Figg, William D., Blagosklonny, Mikhail V.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.32 MB

english, 2011

45

A population pharmacokinetic/toxicity model for the reduction of platelets during a 48-h continuous intravenous infusion of the histone deacetylase inhibitor belinostat

Peer, Cody J., Hall, Oliver M., Sissung, Tristan M., Piekarz, Richard, Balasubramaniam, Sanjeeve, Bates, Susan E., Figg, William D.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 940 KB

english, 2018

46

Precision medicine applications in prostate cancer

McCrea, Edel M., Lee, Daniel K., Sissung, Tristan M., Figg, William D.

Journal:

Therapeutic Advances in Medical Oncology

Year:

2018

Language:

english

File:

PDF, 138 KB

english, 2018

47

CECs and IL-8 Have Prognostic and Predictive Utility in Patients with Recurrent Platinum-Sensitive Ovarian Cancer: Biomarker Correlates from the Randomized Phase-2 Trial of Olaparib and Cediranib Compared with Olaparib in Recurrent Platinum-Sensitive Ovarian Cancer

Lee, Jung-Min, Trepel, Jane B., Choyke, Peter, Cao, Liang, Sissung, Tristan, Houston, Nicole, Yu, Minshu, Figg, William D., Turkbey, Ismail Baris, Steinberg, Seth M., Lee, Min-Jung, Ivy, S. Percy, Liu

Journal:

Frontiers in Oncology

Year:

2015

Language:

english

File:

PDF, 2.16 MB

english, 2015

48

Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis

Fatima, Naheed, Cohen, Devin C., Sukumar, Gauthaman, Sissung, Tristan M., Schooley, James F., Haigney, Mark C., Claycomb, William C., Cox, Rachel T., Dalgard, Clifton L., Bates, Susan E., Flagg, Thoma

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

49

Pilot Study Comparing Systemic and Tissue Pharmacokinetics of Irinotecan and Metabolites after Hepatic Drug-Eluting Chemoembolization

Levy, Elliot B., Peer, Cody, Sissung, Tristan M., Venkatesan, Aradhana, Pandalai, Prakash, Greten, Tim, Hughes, Marybeth S., Garcia, Charisse, Peretti, Julie, Figg, William, Lewis, Andrew, Wood, Bradf

Journal:

Journal of Vascular and Interventional Radiology

Year:

2019

Language:

english

File:

PDF, 131 KB

english, 2019

50

Insulin potentiation therapy for cancer?

Sissung, Tristan M, Schmidt, Keith T, Figg, William D

Journal:

The Lancet Oncology

Year:

2019

Language:

english

File:

PDF, 254 KB

english, 2019